After New York, the fashion world descends on London from today, showcasing big names such as Burberry but also the work of young designers who could become household names of the future.
Last year's event, billed as a comeback after disruption due to the Covid pandemic, was overshadowed by the death of Queen Elizabeth II and 10 days of national mourning.
This year, more than 80 designers are set to present their spring/summer 2024 collections, with around 50 catwalk shows and other presentations.
"It's going to be five really exciting days full of creativity," said Caroline Rush, chief executive of organisers the British Fashion Council (BFC).
Fashion bible Vogue rolled out the red carpet on Thursday night for a gala launch event.
But in the world of fashion, London is enduring a post-Covid slump, with inflation, the highest in the G7 at 6.8% in July, and Brexit combining to create a depressed economic backdrop.
That has left the British capital trailing Paris, Milan and New York in the fashion week stakes.
In a sign of its loss of influence, even British former Spice Girl Victoria Beckham has crossed the Channel to present her designs in Paris since last year.
On Wednesday, the UK government announced £2 million ($2.5 million) to support young designers, which will go to the BFC's existing NewGen programme.
The scheme, which over the last 30 years has supported the best young fashion designers, aims to launch the high-end global brands of tomorrow.
The UK government funding will go towards the staging of five fashion weeks over two years, said the BFC.
Previous recipients include the legendary Alexander McQueen, who died in 2010.
On Saturday, the Design Museum in London is presenting an exhibition celebrating young NewGen talents, and the energy they have brought to the industry.
"REBEL: 30 Years of London Fashion" showcases about 100 designs, some of which have gone down in pop culture history.
This year, about 20 designers are benefiting from the NewGen programme. Most are recent graduates, but who have already managed to dress some of the biggest stars.
Outfits by Ukrainian designer Masha Popova have been worn by singer Dua Lipa. Di Petsa has dressed actress Zendaya.
Among the more established names are 16Arlington, JW Anderson, Molly Goddard, Richard Quinn, Roksanda and Simone Rocha.
But Burberry, the London fashion house founded in 1856, remains the most eagerly awaited show.
It takes place on Monday afternoon and will be only the second collection for British creative director Daniel Lee, following on from his February show.
The ex-Bottega Veneta designer replaced Riccardo Tisci a year ago. Sales have soared in China for the brand with the distinctive check print.
On the final day, Tuesday, Ukrainian designers will present their collections, with London once again hosting Ukrainian Fashion Week due to Russia's invasion.
The BFC is also trying to make London an increasingly inclusive venue for catwalk shows.
It has launched a survey aimed at all those working in the sector, with questions on their gender, sexual orientation, religion, and social background.
"The audit is long overdue and marks the first step towards the vital measurement of the UK fashion industry's collective progress towards the goal of fair representation," the BFC said.
The results will be announced later this year.
Another must-see fashion event in London is the exhibition "Gabrielle Chanel. Fashion manifesto", which opens on Saturday at the V&A museum.
It retraces the 60-year career of "Coco" Chanel, featuring some of her greatest creations that revolutionised women's wardrobes.